Will CBD Make You Tired?

Man resting on couch.

Does CBD make you tired?

The answer is yes. However, the way in which CBD does this does not seem to be through either its interaction with CB1 or CB2 receptors.

Instead, CBD seems to work by affecting the reuptake of adenosine . By inhibiting the reuptake of adenosine, CBD increases the level of adenosine in a brain cell. Adenosine is a "feel good" molecule that attaches to receptors on neurons and slows down the rate at which they fire. If you have a lot of neurons firing slowly, you'll feel tired. If you have more adenosine floating around, you'll feel even sleepier. This is also how caffeine works (another adenosine inhibitor).

CBD has been shown to increase alertness in research studies . So yes, CBD can make you tired. However, it does not appear that this effect is mediated through either CB receptor. And while the research seems to indicate that this is not a problem for CBD users, the long term effects of adenosine receptor inhibition in children and adolescents has not been studied.

What are terpenes?

Terpenes are a type of compound that are found in many plants. These compounds are responsible for the unique smells and flavors of different plants. For example, terpenes are responsible for the piney smell of pine trees and the citrusy smell of oranges.

Terpenes are also believed to have medicinal properties. Some terpenes are thought to be effective at treating anxiety, depression, and other mental health issues. Additionally, terpenes are being studied for their potential to treat cancer and other diseases.

Due to the wide variety of terpenes found in different plants, many of their unique properties are still not yet fully understood. Although more research is needed, it appears that terpenes may soon become a major part of medicine and treatment for mental illness.

3 terpenes that can assist with sleep.


Caryophyllene is a terpene found in plants that is known for its spicy and woody aroma. It is also the primary constituent of essential oils from black pepper, cinnamon, and other spices. This terpene is thought to soothe inflammation, physical pain, and anxiety. The perfect combination for the perfect sleepIt can also be found in cannabis, hops and several citrus plants.

Caryophyllene is one of the most common terpenes; it has a spicy herbal aroma which contributes to black pepper's spiciness, as well as flavors such as cloves, cinnamon, and ginger.

Though not commonly known for its use in supplements, caryophyllene has been used for its medicinal value since the mid 1800s. It is commonly-used in Europe for pain relief and hemp products are now available to American consumers that tout their high caryophyllene content as beneficial to fighting cancer and reducing chronic pain. Caryophyllene shows promise for its anti-inflammatory and antioxidant properties.

Caryophyllene's therapeutic benefit includes reducing chronic pain, fighting cancer, treating anxiety and depression, for skin issues such as eczema or psoriasis, circulatory issues such as improving blood pressure levels and heart health, bronchitis, bowel issues such as IBS and Crohn's disease, and for fighting off neurodegenerative conditions. Many cannabis strains are high in caryophyllene which is why the terpene contributes to the distinctive flavor of the plant.


Nerolidol is a sesquiterpene that can be found in many plants, including ginger, jasmine, and lavender. It has a sweet, woodsy scent and is believed to have calming effects. Nerolidol is thought to be effective in treating anxiety, depression, and other mood disorders. It is also being studied for its potential as a cancer treatment.

Nerolidol may have many beneficial effects on the body. It is thought to fight anxiety, which can cause stress and depression over time. This sesquiterpene may also be able to reduce anxiety that results from medical conditions such as cancer, AIDS, or other chronic illnesses. Nerolidol has even been found to have anti-cancer effects, which is why it's being studied as a potential cancer treatment.

In addition to these benefits, nerolidol has been found to have antioxidant properties that can fight free radicals and prevent diseases such as diabetes and Alzheimer's disease. It may also help to strengthen the immune system and protect against neurodegenerative diseases like Parkinson's and Huntington's disease.


Myrcene is a monoterpene that has a sweet, musky odor. It is found in many essential oils such as hops, lemon grass, verbena, and thyme. It is also found in the cannabis plant. Myrcene is used in aromatherapy and has been shown to be analgesic, anti-inflammatory, and sedative. In the proper dosage, myrcene has been shown to increase the overall effects of THC when taken orally.

Due to its sedative effect, many medical marijuana patients have reported that having a high myrcene level in their body "cured" insomnia and restlessness. Many users found out by accident that this terpene made them drowsy, sometimes to the point of sleepiness. This is one reason patients use cannabis for sleep – because the sedating effect of myrcene could help them fall asleep and stay that way longer.

Another interesting fact about this terpene, though it may seem a bit counter-intuitive for a sedative, is that a high myrcene level in the body could reduce pain. This effect is not common knowledge among medical marijuana patients, but one patient reported that taking a large dose of myrcene before being exposed to high levels of pain helped his mind stay calm enough to keep him from feeling too much discomfort.

He did not feel any sedation while under this high level of pain, but the myrcene helped him stay calm enough to be able to focus on something other than his own discomfort.

This versatile terpene has also been shown to reduce inflammation and help with symptoms such as arthritis and gastrointestinal problems such as irritable bowel syndrome. Some people apply it directly to their skin for pain relief.

Myrcene is a terpene that has not been well-researched, but the preliminary findings suggest that it will play a greater role in medical marijuana treatment options in the future. The sedative aspect of myrcene could be extremely beneficial for people with insomnia and other sleep disorders.

However, because myrcene is found in so many different types of plant essential oils, those who are trying to treat a medical condition with cannabis may want to consult a qualified physician or a pharmacist before they attempt to use myrcene as a treatment.

Know How CBD Effects You.

For some people, CBD causes drowsiness and a loss of alertness. If that is the case for you, it might be a good idea to take CBD before going to sleep.

CBD may also have an effect where one becomes sedated. This sedation may cause problems with memory and learning as well as making certain tasks more difficult.

On the other hand, CBD may keep one awake and alert. For some people, this can make it difficult to go to sleep at night. This is a good reason for making sure that you know how CBD will affect you before using it in any situation where staying alert will be helpful.

In addition to these two opposing results CBD may cause in some people, it is important to remember that CBD is different for everyone. What might be sedating for one person might not be sedating at all another. It's is even difficult to say what effect CBD will have on an individual since so many factors are involved including the cannabinoid profile of the plant, body chemistry and personal history.

If you are taking any medications, especially ones designed to make you drowsy, it is a good idea to avoid CBD altogether. There is a possibility that the sedating effect of these medications and CBD combined could be dangerous. Consult your doctor before taking any new medication in combination with CBD and always inform your doctor about what drugs or supplements you are thinking of taking.

How Do I Know If CBD Will Make Me Tired?

It is always a good idea to start with small doses when trying out any new medication and CBD is no exception. If you have never tried CBD before, it might be a good idea to try some at home before taking it in public or while doing anything important. This way you can see how CBD affects you personally and what you can do to reduce or increase its effects.

Just remember that CBD will not get you "high" in the same way THC does - it is non-psychoactive and does not cause any mind altering effects unless it is taken in extraordinarily large doses.

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